Job Title: Scientist/Senior Scientist Preclinical Development and Translational Science

Work Location: New York County, New York

Summary:

This position focuses on advancing preclinical development and translational science, with an emphasis on oncology biomarkers, cell-based assays, molecular biology, histology, and antibody drug conjugates. The role requires strong collaboration, experimental design, and project management skills to support clinical development initiatives.

Responsibilities:

• Design and implement experimental plans to address key translational questions supporting clinical development strategies.
• Oversee and coordinate studies conducted at external research organizations, ensuring project milestones are met.
• Develop, execute, and validate new and existing assays for biomarker applications in clinical research.
• Align activities and timelines with development teams to ensure effective integration of biomarker capabilities in clinical trials.
• Collaborate with team members to analyze, interpret, and communicate translational research findings.
• Prepare scientific documents, including presentations, biomarker reports, and regulatory submission materials.
• Apply expertise in antibody drug conjugate biology and conduct both in vitro and in vivo ADC testing.
• Manage external projects from initial scoping through to final data delivery, ensuring quality and compliance.

Qualifications:

• MS in a related scientific field; PhD preferred but not required.
• Minimum 2 years of industry experience in preclinical development and clinical oncology biomarker research.
• At least 5 years of hands-on laboratory experience with cell-based assays, molecular biology, and histology; in vivo mouse experience preferred.
• Comprehensive knowledge of antibody drug conjugate biology and experience with both in vitro and in vivo ADC testing.
• Proven ability to develop and validate biomarker assays suitable for clinical samples.
• Demonstrated success in managing external projects with contract research organizations from initiation to data delivery.
• Understanding of the drug development process from target identification through to marketing authorization.
• Basic knowledge of regulatory requirements for medical diagnostics.
• Strong communication, organizational, and problem-solving abilities.

Published Category: Discovery Research & Preclinical