Clinical Site Liaison (Manager/Senior Manager)

Job Title: Clinical Site Liaison (Manager/Senior Manager)

Work Location: Massachusetts

Summary:

The Clinical Site Liaison (Manager/Senior Manager) acts as a field-based resource and extension of Clinical Operations, supporting clinical development programs by partnering with internal teams, CROs, and investigator sites. This role is responsible for fostering strong relationships with clinical trial investigators and site personnel, ensuring high-quality and timely study execution, and serving as a key liaison to support patient access to clinical trials.

Responsibilities:

• Drive site activation and startup timelines by supporting CRO partners, tracking site-level progress, and identifying risks to study delivery.
• Oversee site start-up activities from feasibility through closeout, ensuring regulatory alignment and site readiness in collaboration with study teams and CROs.
• Develop and maintain strong relationships with clinical trial investigators and site staff to enhance engagement and study conduct.
• Partner with CROs to manage site communications, resolve issues, and ensure compliance with ICH GCP, protocol, and operational standards.
• Monitor site performance metrics such as activation timelines, recruitment, and data quality, and collaborate with teams to address challenges and improve outcomes.
• Support recruitment and retention strategies by identifying enrollment barriers and contributing to patient-centered solutions with CROs and sites.
• Participate in study-related activities, including Site Initiation Visits, Investigator Meetings, and CRO/site interactions to support study delivery and relationship building.
• Contribute to internal process improvements, share lessons learned, and support audit and inspection readiness in collaboration with study teams and CROs.

Qualifications:

• Bachelor’s Degree (health sciences or related field preferred).
• 5+ years (Manager) or 7+ years (Senior Manager) of clinical research experience in pharmaceutical or biotechnology settings, with exposure to clinical operations, site management, and/or monitoring.
• Experience in site engagement, clinical operations, or monitoring.
• Ability to communicate scientific and medical information to diverse audiences and translate research objectives into clear operational plans.
• Strong vendor management skills and experience developing or implementing processes and performance indicators.
• Excellent written and verbal communication, collaboration, interpersonal, and organizational skills.
• Ability to resolve issues independently and escalate when necessary; strong stakeholder management skills.
• Knowledge of local and FDA regulatory requirements and ICH GCPs.
• Demonstrated ability to motivate and integrate project teams.
• Passion for advancing research to help patients with unmet medical needs, along with humility and a proactive attitude.
• Willingness to travel approximately 35% for site engagement, meetings, and conferences.

Published Category: Clinical Operations & Development