Job Title: Scientist - Discovery Immunology (Contractor)

Work Location: Grafton County, New Hampshire

Summary:

Seeking a driven and experienced Scientist to join a research team focused on developing next-generation antibody-targeted siRNA/ASO therapeutics for chronic inflammatory and autoimmune diseases. This role offers the opportunity to make significant scientific contributions in a dynamic environment, with high visibility and impact on strategic direction.

Responsibilities:

• Design, establish, and execute immunological assays, including cell culture, functional assays, and flow cytometry, to support hit-to-lead and lead optimization efforts.
• Participate in tissue collection and perform downstream cell-based assays to characterize therapeutic candidates.
• Generate, analyze, and communicate high-quality, well-documented experimental data to inform real-time project decisions.
• Maintain meticulous documentation and ensure data integrity throughout all research activities.
• Proactively communicate project progress, anticipate challenges, and recommend resource allocation as needed.
• Collaborate effectively with internal teams and external partners to advance research objectives and project milestones.
• Contribute to the characterization of new conjugated therapeutics, elucidation of mechanisms of action, and proof-of-concept studies.
• Demonstrate adaptability and initiative in a fast-paced, team-oriented research environment.

Qualifications:

• Ph.D. in Immunology, Biochemistry, Molecular Biology, or a related scientific discipline, or MS with 4+ years of relevant experience in biotechnology or pharmaceutical settings.
• Extensive hands-on experience with immunological techniques, including immune cell isolation, flow cytometry, and T/B/myeloid cell functional assays (e.g., Th1/Th2 T cell assays, ELISA).
• Proficiency in nucleic acid biology and manipulation, including reporter assays, ASO or siRNA approaches, and qRT-PCR.
• Strong problem-solving skills, scientific curiosity, and a goal-oriented mindset with high accountability and initiative.
• Excellent communication, attention to detail, and interpersonal skills.
• Demonstrated ability to work productively in dynamic, cross-functional teams, both internally and externally.
• Outstanding organizational abilities and a collaborative, tactful, and results-driven working style.
• Ability to thrive as a self-starter in a fast-paced, small team environment.

Published Category: Discovery Research & Preclinical